Cuba Sanctions Escalation: The U.S. Treasury and State Department hit Cuba again, imposing new sanctions on President Miguel Díaz-Canel, his wife Lis Cuesta Peraza, and his stepson, plus Alejandro Castro Espín and other figures tied to Raúl Castro, while also targeting key institutions including Cuba’s Ministry of the Revolutionary Armed Forces, ICAP, the Committees for the Defense of the Revolution, and entities like Amistur Cuba and Minera La Victoria. Havana condemned the move, saying it’s meant to reinforce the blockade and intensify conflict. Visa/Mastercard Disruption: Separate reporting says Visa and Mastercard payment services will stop functioning in Cuba starting June 6, adding pressure to an already strained economy. Tourism Under Pressure: As sanctions bite, foreign hotel operators are pulling back—Spain’s Meliá is reported to be shutting down operations at multiple Cuba hotels, following earlier exits by other chains. Rubio’s Transition Talk: Marco Rubio told lawmakers there may be “technocrats” inside Cuba who could play a role in a transition, but he wouldn’t name anyone. Guantánamo Leadership Change: At Guantánamo Bay, U.S. Navy medical command leadership changed hands in a change-of-command ceremony, underscoring ongoing U.S. military medical operations.